Endocrine Abstracts

Introduction: The Short Synachten Test (SST) is the gold standard test for assessing adrenal insufficiency, however these can be time and resource consuming. Improved cortisol assays (Scottish consensus) currently advise a cut-off of 430 nmol/l at 30 minutes . However, there is no clarity about the optimum baseline cortisol level and recommendations range varies from 300–500 nmol/l.The aim of this study was to establish a single baseline cortisol c...

A 39 year-old man was referred with weight loss and lethargy in 2011. On examination tremor, goitre and mild orbital oedema were present. His past medical history consisted of hypertension (ongoing treatment). Investigations: fT4: 37 pmol/l (9–21), TSH: 0.00 mU/l (0.20–4.50), Anti Thyroid Peroxidase: 242.6 U/ml (0–50) and TRAbs: 11.2 iu/l (0–1.6). Graves’ thyrotoxicosis with moderately active eye disease was diagnosed and he started on carbimazole and ...